Novel 3-N-aminoglycoside acetyltransferase gene, aac(3)-Ic, from a Pseudomonas aeruginosa integron.

نویسندگان

  • Maria Letizia Riccio
  • Jean-Denis Docquier
  • Emanuela Dell'Amico
  • Francesco Luzzaro
  • Gianfranco Amicosante
  • Gian Maria Rossolini
چکیده

A novel gene, aac(3)-Ic, encoding an AAC(3)-I aminoglycoside 3-N-acetyltransferase, was identified on a gene cassette inserted into a Pseudomonas aeruginosa integron that also carries a bla(VIM-2) and a cmlA7 gene cassette. The aac(3)-Ic gene product is 59 and 57% identical to AAC(3)-Ia and AAC(3)-Ib, respectively, and confers resistance to gentamicin and sisomicin.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 47 5  شماره 

صفحات  -

تاریخ انتشار 2003